The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2005

Filed:

Jul. 24, 2000
Applicants:

Pradip Mukerji, Gahanna, OH (US);

Tapas Das, Worthington, OH (US);

Yung-sheng Huang, Upper Arlington, OH (US);

Jennifer M. Parker-barnes, New Albany, OH (US);

Amanda Eun-yeong Leonard, Gahanna, OH (US);

Jennifer Thurmond, Columbus, OH (US);

Inventors:

Pradip Mukerji, Gahanna, OH (US);

Tapas Das, Worthington, OH (US);

Yung-Sheng Huang, Upper Arlington, OH (US);

Jennifer M. Parker-Barnes, New Albany, OH (US);

Amanda Eun-Yeong Leonard, Gahanna, OH (US);

Jennifer Thurmond, Columbus, OH (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N009/00 ; C12N005/00 ; C12N001/20 ; C12N015/00 ; C12P021/06 ;
U.S. Cl.
CPC ...
Abstract

The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated acids (i.e., 'elongases') and to uses thereof. At least two of these genes are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogama linolenic acid (DGLA) and in the conversion of DGLA or 20:4n-3 to eicosapentaenoic acid (EPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachiodonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid, ω6-docosapentaenoic acid or ω3-docosapentaenoic acid which may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.


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