The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2005
Filed:
Jan. 09, 2003
Shin-ichi Yokota, Hyogo, JP;
Kozo Yamamoto, Osaka, JP;
Souichi Morikawa, Hyogo, JP;
Yoshihide Fuse, Hyogo, JP;
Mikio Kitahara, Hyogo, JP;
Shin-ichi Yokota, Hyogo, JP;
Kozo Yamamoto, Osaka, JP;
Souichi Morikawa, Hyogo, JP;
Yoshihide Fuse, Hyogo, JP;
Mikio Kitahara, Hyogo, JP;
Kaneka Corp., , JP;
Abstract
A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor. The novel compound benzo-1,3-dioxole provides an inhibitor of HSF activity or an inhibitor of inducing the production of a protein regulated by HSF, which inhibits the activity of a heat shock factor, a transcriptional regulatory factor, thereby in turn inhibiting transcription of a structural gene having a heat shock element sequenc in the gene region for transcriptional regulation into RNA, and thus inhibiting translation of the gene into a protein, and resulting in inhibition of inducing production of RNA or protein encoded by the gene. It also provides a drug for treating or preventing cancer through thermotherapy and a drug for treating or preventing stress diseases such as depression.