The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2005
Filed:
Aug. 23, 2002
Igor P. Smirnov, Brookline, MA (US);
Andrew J. Tomlinson, Wayland, MA (US);
Lawrence A. Haff, Westborough, MA (US);
Jennifer M. Campbell, Somerville, MA (US);
Cheryl E. Murphy, Hudson, NH (US);
Igor P. Smirnov, Brookline, MA (US);
Andrew J. Tomlinson, Wayland, MA (US);
Lawrence A. Haff, Westborough, MA (US);
Jennifer M. Campbell, Somerville, MA (US);
Cheryl E. Murphy, Hudson, NH (US);
PerSeptive BioSystems, Inc., Framingham, MA (US);
MDS Inc., Toronto, CA;
Abstract
A sample plate for a MALDI process is provided which comprises an electrically conductive substrate having a hydrophobic coating whose thickness and hydrophobic character can be modified by changing the coating substrate and/or the concentration of the substrate. Different coating substances that have provided optimal performance of the sample plate for reproducible deposition and analysis by MALDI-MS and MALDI-MS/MS processes of analyte mixtures include synthetic waxes such as paraffin compositions, lipids, organic acids, silicon-containing compounds, silica polymers and natural waxes. Metal polishes that have been used to clean and regenerate plate surfaces have also provided a sample plate that has optimal performance for reproducible deposition and analysis by MALDI-MS and MALDI-MS/MS processes of analyte mixtures.