The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2005
Filed:
Apr. 28, 2003
Janet L. Rideout, Fuquay-Varina, NC (US);
Benjamin R. Yerxa, Raleigh, NC (US);
Sammy Ray Shaver, Chapel Hill, NC (US);
James G. Douglass, Iii, Apex, NC (US);
Janet L. Rideout, Fuquay-Varina, NC (US);
Benjamin R. Yerxa, Raleigh, NC (US);
Sammy Ray Shaver, Chapel Hill, NC (US);
James G. Douglass, III, Apex, NC (US);
Inspire Pharmaceuticals, Inc., Durham, NC (US);
Abstract
The present invention relates to certain novel dinucleoside polyphosphates of general Formulae I, II and III, and formulations thereof which are selective ligands of the P2Y purinergic receptors. Applicants have discovered that dinucleoside polyphosphates of general Formulae I, II and III are effective in clearing retained mucous secretions, balancing tissue hydration and fluid secretion, and/or inhibiting or preventing early stages of platelet activation, platelet degranulation, and platelet aggregation.