Titanium catalyst and organotitanium reacting reagent, production thereof, and reaction thereby

Abstract

A titanium catalyst for reaction between a compound having a carbon-carbon unsaturated bond and a compound having an electrophilic functional group or an electrophilic reagent, said titanium catalyst being composed of a titanium compound represented by the formula (1) belowTiXXXX  (1)(where X, X, X, and Xdenote independently a halogen atom, Calkoxyl group, aralkyloxy group, aryloxy group, or —NRxRy group (where Rx and Ry denote independently a Calkyl group or aralkyl group), and any two of X, X, X, and Xmay form a ring.) and a Grignard reagent represented by the formula (2) below in a molar amount 1.5-2.5 times as much as the titanium compound.RMgX  (2)(where Rdenotes a Calkyl group having a hydrogen atom at the β position and Xdenotes a halogen atom.) The titanium catalyst of the present invention activates the carbon-carbon unsaturated bond, which has a comparatively low reactivity, thereby catalyzing the reaction with an electrophilic functional group. It is inexpensive and industrially advantageous. When applied to reaction between a compound having a carbon-carbon unsaturated bond and an electrophilic functional group, it yields industrially a variety of adducts of a compound having a carbon-carbon unsaturated bond and a compound having an electrophilic functional group, and it also yields a variety of intramolecular adducts of a compound having a carbon-carbon unsaturated bond and an electrophilic functional group in the same molecule.