The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2005
Filed:
Jul. 09, 2002
Paul F. Worley, Baltimore, MD (US);
Jian Cheng Tu, Baltimore, MD (US);
BO Xiao, Ellicott City, MD (US);
Daniel Leahy, Baltimore, MD (US);
Jutta Beneken, Baltimore, MD (US);
Anthony A. Lanahan, Baltimore, MD (US);
Paul R. Brakeman, Baltimore, MD (US);
Paul F. Worley, Baltimore, MD (US);
Jian Cheng Tu, Baltimore, MD (US);
Bo Xiao, Ellicott City, MD (US);
Daniel Leahy, Baltimore, MD (US);
Jutta Beneken, Baltimore, MD (US);
Anthony A. Lanahan, Baltimore, MD (US);
Paul R. Brakeman, Baltimore, MD (US);
Other;
Abstract
A method is provided for identifying a compound that modulates a cellualr response associate with Homer and mediated by a cell-surface or an intracellular receptor. A method is further provided for identifying a compound that modulates receptor activated calcium mobilization associated with Homer. A method is provided for identifying a compound that inhibits Homer protein activity based on the crystal structure coordinates of Homer protein binding domain. A method is also provided for identifying a compound that affects the formation of cell surface receptors into clusters. Also provided are nucleic acids encoding Homer proteins as well as Homer proteins, and Homer interacting proteins.