The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2005

Filed:

Oct. 03, 2002
Applicants:

George J. Piazza, Meadowbrook, PA (US);

Thomas A. Foglia, Lafayette Hill, PA (US);

Alberto Nunez, Dresher, PA (US);

Inventors:

George J. Piazza, Meadowbrook, PA (US);

Thomas A. Foglia, Lafayette Hill, PA (US);

Alberto Nunez, Dresher, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K038/43 ; A61K035/78 ; C12P017/02 ; C12N011/08 ;
U.S. Cl.
CPC ...
Abstract

A method has been discovered for the epoxidation of a compound having at least one carbon-carbon double bond, the method involves reacting a compound having at least one carbon-carbon double bond, a solvent, an oxidant, and membrane bound peroxygenase. Also discovered is a method for preparing the membrane bound peroxygenase involving grinding seeds containing peroxygenase to produce ground seeds, homogenizing the ground seeds in a buffer to form a slurry, centrifuging the slurry to produce a first supernatant, centrifuging the first supernatant to produce a second supernatant, and filtering said second supernatant through a protein-binding membrane filter to produce membrane bound peroxygenase; optionally the second supernatant is filtered through a hydrophilic membrane filter prior to filtering the second supernatant through a protein-binding membrane filter.


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