The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2005
Filed:
Oct. 10, 2000
Kurt Haas, Goshen, NY (US);
Wun Chey Sin, Huntington, NY (US);
Ashkan Javaherian, Huntington, NY (US);
Zheng LI, Huntington, NY (US);
Hollis Cline, Cold Spring Harbor, NY (US);
Kurt Haas, Goshen, NY (US);
Wun Chey Sin, Huntington, NY (US);
Ashkan Javaherian, Huntington, NY (US);
Zheng Li, Huntington, NY (US);
Hollis Cline, Cold Spring Harbor, NY (US);
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);
Abstract
A single cell electroporation assembly and method involve delivery of a substance into a single cell. The substance is combined into an electroporation fluid and placed into a container having a distal opening. The distal opening of the container is placed in proximity to a target cell. Electrical pulses are delivered between a first electrode which is at least partially disposed in the container, and a second electrode outside the cell, the cell being positioned between the distal opening and the second electrode. The electrical pulses induce temporary formation of pores in the cell membrane and the substance enters the cell through the pores by passive diffusion or by active electrophoretic motion.