The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2005

Filed:

Apr. 14, 1999
Applicants:

Laurent Chevalet, Annemasse, FR;

Alain Robert, Annemasse, FR;

Jean-yves Bonnefoy, Le Sappey, FR;

Thien Ngoc Nguyen, Saint Julien en Genevois, FR;

Inventors:

Laurent Chevalet, Annemasse, FR;

Alain Robert, Annemasse, FR;

Jean-Yves Bonnefoy, Le Sappey, FR;

Thien Ngoc Nguyen, Saint Julien en Genevois, FR;

Assignee:

Pierre Fabre Medicament, Castres Cedex, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 2106 ; C12P 2104 ; C12N 120 ; C12N 1574 ;
U.S. Cl.
CPC ...
Abstract

The invention concerns a novel construct for expressing a gene coding for a recombinant protein of interest placed under the control of the Ptrp tryptophan operon promoter in a procaryotic host cell. The invention is characterised in that the construct comprises a nucleic sequence capable of inactivating the gene coding for a TnaA tryptophanase when said nucleic sequence is introduced in said host cell. The invention also concerns vectors containing said construct and host cells transformed by said vectors. The invention further concerns methods for producing said recombinant proteins using said novel constructs.


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