The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2004
Filed:
Sep. 19, 2001
Applicant:
Inventors:
Andrew L. Niles, Madison, WI (US);
Mary Haak-Frendscho, Newark, CA (US);
Jennifer L. Harris, San Diego, CA (US);
Charles S. Craik, San Francisco, CA (US);
Assignee:
Promega Corporation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 ; A61K 3/807 ; C07K 5/10 ;
U.S. Cl.
CPC ...
C12Q 1/00 ; A61K 3/807 ; C07K 5/10 ;
Abstract
The invention is directed to synthetic polypeptide substrates for tryptase enzymes and assays for tryptase activity that utilize the synthetic polypeptide substrates. The preferred synthetic polypeptide substrates are tetramers of the formula P4-P3-P2-P1, wherein the substrate is selected from the group consisting of P-R-N-K (SEQ. ID. NO: 2), P-K-N-K (SEQ. ID. NO: 3), P-R-N-R (SEQ. ID. NO: 4), P-K-N-R (SEQ. ID. NO: 5), P-A-N-K (SEQ. ID. NO: 6), and P-R-T-K (SEQ. ID. NO: 7).