The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2004

Filed:

Jan. 09, 2001
Applicant:
Inventors:

Mitsuhiro Ueno, Kusatsu, JP;

Hirofumi Yoshioka, Kusatsu, JP;

Haruko Konishi, Kyoto, JP;

Kimikazu Hashino, Takatsuki, JP;

Mio Morishita, Otsu, JP;

Hideto Chono, Moriyama, JP;

Tsuyoshi Miyamura, Kusatsu, JP;

Mutsumi Sano, Otsu, JP;

Kiyozo Asada, Shiga, JP;

Kei Fujinaga, Otsu, JP;

Ikunoshin Kato, Uji, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/563 ; C12N 1/587 ;
U.S. Cl.
CPC ...
C12N 1/563 ; C12N 1/587 ;
Abstract

Improved methods for transferring a gene into target cells by using a retrovirus, wherein the gene transfer efficiency is improved and the target cells are efficiently transformed by binding the retrovirus to a functional substance which is immobilized on as carrier and having an activity of binding to retroviruses followed by washing; using an antibody capable of specifically recognizing cells, laminin or mannose-rich type sugar chain as a substance having an activity of binding to the target cells; pre-treating the target cells so as to inactivate transferrin receptor, or introducing a new functional group into the functional substance.


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