The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2004
Filed:
Dec. 10, 2001
Applicant:
Inventors:
Noboru Yamaji, Ibaraki, JP;
Kouichi Nishimura, Ibaraki, JP;
Kunitake Abe, Ibaraki, JP;
Osamu Ohara, Chiba, JP;
Takahiro Nagase, Chiba, JP;
Nobuo Nomura, Chiba, JP;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/48 ; C12N 1/500 ; C12N 1/20 ; C12P 2/104 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 9/48 ; C12N 1/500 ; C12N 1/20 ; C12P 2/104 ; C07H 2/104 ;
Abstract
This invention provides a novel metalloprotease having an aggrecanase activity which causes joint diseases, a gene coding for this metalloprotease, a promoter of the above metalloprotease, a method for screening a drug with the use of the above metalloprotease and a pharmaceutical composition for inhibiting degradation of proteoglycans, which comprises as the active ingredient a substance capable of inhibiting the aggrecanase activity of the above metalloprotease.