The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2004
Filed:
May. 25, 2001
James Thompson, Lafayette, CO (US);
Leonid Beigelman, Longmont, CO (US);
James McSwiggen, Boulder, CO (US);
Alexander Karpeisky, Lafayette, CO (US);
Laurent Bellon, Frederick, MD (US);
Mark Reynolds, Pleasanton, CA (US);
Michael Zwick, Madison, WI (US);
Thale Jarvis, Boulder, CO (US);
Tod Woolf, Sudbury, MA (US);
Peter Haeberli, Berthoud, CO (US);
Jasenka Matulic-Adamic, Boulder, CO (US);
Sirna Therapeutics, Inc., Boulder, CO (US);
Abstract
This invention relates to novel chemically-modified nucleic acid molecules having specific formulae that exhibit increased resistance to nucleases and increased binding affinity to target nucleic acid molecules. The invention further relates to methods of modulating gene expression using the novel chemically modified nucleic acid molecules, and compositions and cells comprising said molecules.