The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2003

Filed:

Aug. 04, 2000
Applicant:
Inventors:

Kevin D. Nelson, Arlington, TX (US);

Andres A. Romero-Sanchez, Arlington, TX (US);

George M. Smith, Lexington, KY (US);

Nadir Alikacem, Allen, TX (US);

Delia Radulescu, Arlington, TX (US);

Paula Waggoner, Burleson, TX (US);

Zhibing Hu, Denton, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/02 ; A61K 4/730 ;
U.S. Cl.
CPC ...
A61F 2/02 ; A61K 4/730 ;
Abstract

The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal distribution of released therapeutic agents is controlled by use of defined nonhomogeneous patterns of therapeutic agents in the matrices.

Published as:
CA2379909A1; WO0110421A1; AU6526100A; EP1206254A1; CN1378445A; JP2003506401A; US6596296B1; US2003203003A1; US6858222B2; US2005106211A1; US7514095B2; CA2379909C; JP2011255197A; JP4859317B2; CN1378445B; JP5383757B2;

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