The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2003
Filed:
Jul. 17, 2000
Applicant:
Inventors:
Xiaoqun Jiang, Quincy, MA (US);
E. Antonio Chiocca, Wakefield, MA (US);
Elliott Kieff, Brookline, MA (US);
Fred Wang, Chestnut Hill, MA (US);
Fred Hochberg, Chestnut Hill, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/500 ; C12N 1/509 ; C12N 1/563 ; C12N 1/570 ; C12N 1/574 ;
U.S. Cl.
CPC ...
C12N 1/500 ; C12N 1/509 ; C12N 1/563 ; C12N 1/570 ; C12N 1/574 ;
Abstract
The present invention relates to a viral vector system derived from Epstein-Barr Virus (EBV), where the transgene is effectively inserted into the EBV major internal repeat region (IR1) without adverse affect on EBV latent or lytic function. The vector of the invention can target and stably transform B-lymphocyte cells, both in culture and in vivo.