The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2003
Filed:
May. 13, 1997
Applicant:
Inventors:
Darell D. Bigner, Mebane, NC (US);
John H. Sampson, Durham, NC (US);
David M. Ashley, Victoria, AU;
Laura P. Hale, Hillsborough, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 4/800 ; C12N 1/587 ; C12N 5/02 ; C12N 1/563 ;
U.S. Cl.
CPC ...
A61K 4/800 ; C12N 1/587 ; C12N 5/02 ; C12N 1/563 ;
Abstract
Vaccination with an allogeneic cell line modified with genetic material encoding specific protein antigens is an effective technique for the delivery of protein antigens to the host's antigen presentation system. The immune response generated by this vaccine is restricted by the major histocompatibility complex type of the host and not the vaccinating cell line. This immunization strategy may be used to treat or prevent tumors or infectious diseases of a mammal.