The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2002

Filed:

Jun. 29, 1999
Applicant:
Inventors:

Daniel C. Tessier, Pierrefonds, CA;

Andrë Zapun, Fontanil, FR;

John J. M. Bergeron, Pointe Claire, CA;

David Y. Thomas, Montreal West, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/00 ; C07K 2/00 ; C12N 1/509 ;
U.S. Cl.
CPC ...
C07K 1/00 ; C07K 2/00 ; C12N 1/509 ;
Abstract

The present invention relates to methods of treating and diagnosing protein trafficking disorders and controlling secretory protein production. The present invention also relates to methods for folding unfolded proteins, especially in heterelogous expression systems. The methods comprise exposing an unfolded protein to a biological preparation comprising ERp57 in combination with calnexin or calreticulin under conditions to permit folding of the unfolded protein.


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