The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2002

Filed:

Aug. 23, 2000
Applicant:
Inventors:

In Suk Han, Salt Lake City, UT (US);

You Han Bae, Salt Lake City, UT (US);

Dal Young Jung, Salt Lake City, UT (US);

Jules John Magda, Salt Lake City, UT (US);

Assignee:

M-Biotech, Inc., Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/54 ;
U.S. Cl.
CPC ...
C12Q 1/54 ;
Abstract

A biosensor ( ) has a hydrogel ( ) in a rigid and referably biocompatible enclosure ( ). The hydrogel ( ) includes an immobilized glucose-binding molecule such as concanavalin A (Con A) and an immobilized hexose saccharide such as a-D-mannopyranoside. The immobilized hexose saccharide competitively binds with free glucose to the glucose-binding molecules, thus changing the number of crosslinks in the hydrogel ( ), which changes hydrogel swelling tendency and the pressure of the hydrogel in its confined space in proportion to the concentration of free glucose. By measuring the change in hydrogel pressure with a pressure transducer ( ), the biosensor ( ) is able to accurately measure the concentration of the tree glucose molecule without the problem of oxygen limitations and interference encountered by prior art biosensors. A battery ( ) powered telemeter ( ) operably engaged to the pressure transducer ( ) sends a radio data signal to a receiver ( ) containing an alarm system operably attached to a computer ( ). Furthermore, an alarm system utilizes such a sensor to automatically notify a person that the blood glucose level is outside a predetermined parameter, and/or to automatically inject an agent such as glucose or glycogen which will raise blood glucose levels.

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