The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2002
Filed:
Mar. 11, 1999
Applicant:
Inventors:
Richard F Selden, Wellesley, MA (US);
Marianne Borowski, Winthrop, MA (US);
Carol M. Kinoshita, Bedford, MA (US);
Douglas A. Treco, Arlington, MA (US);
Melanie D. Williams, Natick, MA (US);
Thomas J. Schuetz, Framingham, MA (US);
Peter F. Daniel, Natick, MA (US);
Assignee:
Transkaryotic Therapies, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/40 ; A61K 3/843 ;
U.S. Cl.
CPC ...
C12N 9/40 ; A61K 3/843 ;
Abstract
The invention provides highly purified &agr;-Gal A, and various methods for purifying it; &agr;-Gal A preparations with altered charge and methods for making those preparations; &agr;-Gal A preparations that have an extended circulating half-life in a mammalian host, and methods for making same; and methods and dosages for administering an &agr;-Gal A preparation to a subject.