The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2002
Filed:
May. 14, 1998
Applicant:
Inventors:
Hui Zheng, Edison, NJ (US);
Ping Jiang, Trenton, NJ (US);
Su Qian, Sayreville, NJ (US);
Leonardus H. T. Van Der Ploeg, Scotch Plains, NJ (US);
Philip Chun-Ying Wong, Timonium, MD (US);
Sangram S. Sisodia, Chicago, IL (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 6/700 ; A01K 6/7033 ; A01K 6/7027 ; C12N 1/500 ; C12Q 1/02 ;
U.S. Cl.
CPC ...
A01K 6/700 ; A01K 6/7033 ; A01K 6/7027 ; C12N 1/500 ; C12Q 1/02 ;
Abstract
The present invention relates to a transgenic non-human animal embryo lacking native presenilin 1 and a transgenic non-human animal having only a non-native presenilin 1. The transgenic animals and cells derived therefrom can be used in the study of the expression pattern, activity and modulators of presenilin 1, in the study of the role of presenilin 1 in Alzheimer's Disease and in the study of disorders of the central nervous system.