The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2002
Filed:
Mar. 25, 1999
Applicant:
Inventors:
John F. Engelhardt, Iowa City, IA (US);
Dongsheng Duan, Iowa City, IA (US);
Assignee:
University of Iowa Research Foundation, Iowa City, IA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 4/800 ; C12N 1/5864 ; C12N 1/563 ; C12N 1/564 ;
U.S. Cl.
CPC ...
A61K 4/800 ; C12N 1/5864 ; C12N 1/563 ; C12N 1/564 ;
Abstract
The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.