The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2002

Filed:

Dec. 22, 1999
Applicant:
Inventors:

Alan B. Cooper, West Caldwell, NJ (US);

Ronald J. Doll, Maplewood, NJ (US);

Johan A. Ferreira, Bensalem, PA (US);

Ashit Ganguly, Upper Montclair, NJ (US);

Viyyoor M. Girijavallabhan, Parsippany, NJ (US);

Arthur G. Taveras, Denville, NJ (US);

Jianping Chao, Summit, NJ (US);

John J. Baldwin, Gwynedd Valley, PA (US);

Chia-Yu Huang, Plainsboro, NJ (US);

Ge Li, Lawrenceville, NJ (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1496 ; C07D / ; C07D / ; C07D / ; A61P 3/500 ;
U.S. Cl.
CPC ...
A61K 3/1496 ; C07D / ; C07D / ; C07D / ; A61P 3/500 ;
Abstract

Novel compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammals such as a human.


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