The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2002

Filed:

Dec. 20, 1995
Applicant:
Inventors:

Jonathan M. Graff, Newton, MA (US);

Tod M. Woolf, Natick, MA (US);

Ping Jin, Boston, MA (US);

Douglas A. Melton, Lexington, MA (US);

Assignee:

Curis, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/512 ; C12N 1/562 ; C07K 1/446 ; C07K 1/900 ;
U.S. Cl.
CPC ...
C12N 1/512 ; C12N 1/562 ; C07K 1/446 ; C07K 1/900 ;
Abstract

The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here signalin-related genes, which are involved in signal transduction induced by members of the TGF&bgr; superfamily. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.


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