The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2002

Filed:

Feb. 05, 1999
Applicant:
Inventors:

Marja Liisa Alajoki, Palo Alto, CA (US);

H. Garrett Wada, Atherton, CA (US);

Robert S. Dubrow, San Carlos, CA (US);

Assignee:

Caliper Technologies Corp., Mountain View, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 2/726 ; B01L 3/00 ;
U.S. Cl.
CPC ...
G01N 2/726 ; B01L 3/00 ;
Abstract

Apparatus and methods for modulating flow rates in microfluidic devices are provided. The methods involve modulating downstream pressure in the device to change the flow rate of materials in an upstream region of the device. Such methods include electrokinetic injection or withdrawal of materials through a side channel and the use of an absorbent material to induce wicking in the channel system. The apparatus provided includes a prefabricated wick in the device to provide for flow rate control. Additional methods for determining velocity of a particle and cell incubation time are also provided.

Published as:
CA2353998A1; WO0043766A1; AU2512500A; EP1153285A1; US6416642B1; EP1153285A4; US2002179445A1; AU762045B2; AU2003248199A1; AU2003248199B2; US6989128B2; EP1153285B1;

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