The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2002
Filed:
May. 01, 1998
Applicant:
Inventors:
Susanna M. Rybak, Frederick, MD (US);
Dianne L. Newton, Rockville, MD (US);
David M. Goldenberg, Mendham, NJ (US);
Assignee:
Immunomedics, Inc., Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/9395 ; A61K 3/800 ; A61K 3/9385 ; A61K 3/900 ; C12P 2/108 ;
U.S. Cl.
CPC ...
A61K 3/9395 ; A61K 3/800 ; A61K 3/9385 ; A61K 3/900 ; C12P 2/108 ;
Abstract
The present invention relates to immunotoxins, that effectively kill malignant cells having a given surface marker and nucleic acid constructs encoding them. These reagents comprise a toxic moiety that is derived from a protein having ribonucleolytic activity linked to an antibody capable of specific binding with a chosen tumor cell.