The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2002
Filed:
Nov. 25, 1998
Applicant:
Inventor:
Klaus-Peter Radtke, Apex, NC (US);
Assignee:
Bayer Corporation, Pittsburgh, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/846 ; C12N 9/16 ; C12N 1/20 ; C07K 2/104 ; C07K 1/600 ;
U.S. Cl.
CPC ...
A61K 3/846 ; C12N 9/16 ; C12N 1/20 ; C07K 2/104 ; C07K 1/600 ;
Abstract
The invention is directed to a method of decreasing atheroma formation in a mammal comprising administering a pharmaceutically effective amount of PON-1 or its functional equivalent to a patient in need thereof. Also included herein are pharmaceutical compositions, and a method for diagnosing predisposition to hypercholesterolemia by assessing the level of native circulating PON-1.