The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2002
Filed:
Jun. 07, 1995
Mark J. Evans, Cheshire, CT (US);
Louis A. Matis, Southport, CT (US);
Eileen Elliott Mueller, East Haven, CT (US);
Steven H. Nye, Mequon, WI (US);
Scott Rollins, Monroe, CT (US);
Russell P. Rother, Cheshire, CT (US);
Jeremy P. Springhorn, Cheshire, CT (US);
Stephen P. Squinto, Bethany, CT (US);
Thomas C. Thomas, Madison, CT (US);
James A. Wilkins, Woodbridge, CT (US);
Alexion Pharmaceuticals, Inc., Cheshire, CT (US);
Abstract
The use of anti-C5 antibodies, e.g., monoclonal antibodies, to treat glomerulonephritis (GN) is disclosed. The administration of such antibodies at low dosage levels has been found to significantly reduce glomerular inflammation/enlargement and other pathologic conditions associated with GN. Also disclosed are anti-C5 antibodies and anti-C5 antibody-encoding nucleic acid molecules. These antibodies are useful in the treatment of GN and other inflammatory conditions involving pathologic activation of the complement system.