The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2001
Filed:
Sep. 02, 1994
Applicant:
Inventors:
Jan McDonagh, Chestnut Hill, MA (US);
Myoung H. Lee, Brookline, MA (US);
Marcin J. Mankowski, Newton, MA (US);
Assignee:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/56 ;
U.S. Cl.
CPC ...
C12Q 1/56 ;
Abstract
The invention is based upon the discovery that PAI-1 activity of a sample can be measured with sensitivity and correlation to in vivo activity without the use of standard curves. The assay determines the PAI-1 activity of a sample upon utilizing the second order rate equation for the reaction of PAI-1 and t-PA, as measured by their activities, in that sample.