The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2001

Filed:

Mar. 30, 1999
Applicant:
Inventors:

Thomas G. Thundat, Knoxville, TN (US);

K. Bruce Jacobson, Oak Ridge, TN (US);

Mitchel J. Doktycz, Knoxville, TN (US);

Stephen J. Kennel, Oak Ridge, TN (US);

Robert J. Warmack, Knoxville, TN (US);

Assignee:

U. T. Battelle, LLC, Oak Ridge, TN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 1/910 ; G01N 2/902 ; G01N 3/116 ;
U.S. Cl.
CPC ...
G01N 1/910 ; G01N 2/902 ; G01N 3/116 ;
Abstract

A sensor apparatus is provided using a microcantilevered spring element having a coating of a detector molecule such as an antibody or antigen. A sample containing a target molecule or substrate is provided to the coating. The spring element bends in response to the stress induced by the binding which occurs between the detector and target molecules. Deflections of the cantilever are detected by a variety of detection techniques. The microcantilever may be approximately 1 to 200 &mgr;m long, approximately 1 to 50 &mgr;m wide, and approximately 0.3 to 3.0 &mgr;m thick. A sensitivity for detection of deflections is in the range of 0.01 nanometers.


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