The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2001

Filed:

Nov. 27, 1996
Applicant:
Inventors:

Thomas M. Jessell, New York, NY (US);

Jane Dodd, New York, NY (US);

Henk Roelink, New York, NY (US);

Thomas Edlund, Holmsund, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/4475 ;
U.S. Cl.
CPC ...
C07K 1/4475 ;
Abstract

This invention provides an isolated nucleic acid molecule encoding a vertebrate Vhh-1 protein. The preferred embodiments are rat and human Vhh-1 protein. This invention provides purified vertebrate Vhh-1 protein and a method to purify same. This invention provides isolated nucleic acid molecules encoding a human and a rat Vhh-1 protein and the purified rat and human Vhh-1 protein encoded by same. This invention provides a vector encoding a vertebrate Vhh-1 protein and mammalian cells comprising such vectors. This invention provides antibodies directed to a vertebrate Vhh-1 protein. This invention further provides nucleic acid probes useful for detecting a nucleic acid molecule encoding a vertebrate Vhh-1 protein. This invention provides pharmaceutical compounds comprising the human Vhh-1 protein. This invention provides nonhuman transgenic animals which express DNA encoding a vertebrate Vhh-1 protein. This invention provides treatments for alleviating abnormalities associated with the vertebrate Vhh-1 protein.


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