The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2001
Filed:
Sep. 02, 1998
Applicant:
Inventors:
Clarence Frank Bennett, Carlsbad, CA (US);
Muthiah Manoharan, Carlsbad, CA (US);
Normand Hebert, Cardiff by the Sea, CA (US);
Balkrishen Bhat, Carlsbad, CA (US);
Assignee:
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A01N 4/304 ; A01N 6/100 ; C07H 1/900 ; C12Q 1/68 ;
U.S. Cl.
CPC ...
A01N 4/304 ; A01N 6/100 ; C07H 1/900 ; C12Q 1/68 ;
Abstract
The present invention provides improved methods for tracking the biodistribution of macromolecules and carriers in cells. In accordance with one embodiment, oligonucleotides and lipid carriers are differentially fluorescently labeled and coadministered to the cells. Useful compounds and synthetic methods are also provided.