The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2001
Filed:
Jan. 04, 1999
Angus Murray MacLeod, Bishops Stortford, GB;
Graham Andrew Showell, Welwyn Garden City, GB;
Leslie Joseph Street, Harlow, GB;
Merck Sharp & Dohme Ltd., Hertfordshire, GB;
Abstract
A class of substituted aminocyclohexane derivatives are selective agonists of 5-HT,-like receptors, being potent agonists of the human 5-HT,receptor subtype while possessing at least a 10-fold selective affinity for the 5-HT,receptor subtype relative to the 5-HT,subtype; they are therefore useful in the treatment and/or prevention of clinical conditions, in particular migraine and associated disorders, for which a subtype-selective agonist of 5-HT,receptors is indicated, while eliciting fewer side-effects, notably adverse cardiovascular events, than those associated with non-subtype-selective 5-HT,receptor agonists.