The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2001

Filed:

May. 16, 1996
Applicant:
Inventors:

Cynthia Ann Richards, Durham, NC (US);

Brian Huber, Durham, NC (US);

Assignee:

Glaxo Wellcome Inc., Research Triangle Park, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/563 ; C12N 1/5867 ; C12N 5/10 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 1/563 ; C12N 1/5867 ; C12N 5/10 ; C07H 2/104 ;
Abstract

The transcriptional regulatory sequence (TRS) of Carcinoembryonic Antigen (CEA) and molecular chimeras comprising the CEA TRS and DNA encoding a heterologous enzyme are described. Such molecular chimeras are capable of targeting the expression of the heterologous enzyme to CEA-positive cells. The heterologous enzyme may be cytosine deaminase.


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