The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2000

Filed:

Aug. 17, 1999
Applicant:
Inventors:

Camilo Canel, Oxford, MS (US);

Franck E Dayan, Water Valley, MS (US);

Rita M Moraes, Oxford, MS (US);

Charles L Burandt, Oxford, MS (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
4241951 ;
Abstract

Enhanced recovery of podophyllotoxin from biological sources is achieved through disruption or permeabilization of the physical integrity of cells and tissues in the presence of sufficient moisture so as to allow endogenous enzymes to convert podophyllotoxin glucosides to podophyllotoxin. Extraction of the podophyllotoxin from the plant material is then achieved by use of an organic solvent. Podophyllotoxin is used as an intermediate in the production of the antitumor agent etoposide and its analogues.


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