The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2000

Filed:

May. 19, 1995
Applicant:
Inventors:

Roland E Dolle, King of Prussia, PA (US);

Denton W Hoyer, Exton, PA (US);

Tina Morgan Ross, Audubon, PA (US);

James M Rinker, Reading, PA (US);

Stanley J Schmidt, Chester Springs, PA (US);

Mark A Ator, Paoli, PA (US);

Assignee:

Vertex Pharmaceuticals, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
51425203 ; 514241 ; 51425201 ; 51425204 ; 51425205 ;
Abstract

Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein R.sub.1 is a halogen, or an oxygen linked leaving group including an aromatic ether, an alkyl sulfonate, an aryl sulfonate, an alkyl phosphonate, an aryl phosphonate, an alkyl phosphate or aryl phosphate;


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