The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2000

Filed:

Jan. 24, 1995
Applicant:
Inventors:

Bradford A Jameson, Philadelphia, PA (US);

Mariadele Noe, Haddonfield, NJ (US);

Assignee:

Thomas Jefferson University, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
514-9 ; 514 11 ; 514 12 ; 514 13 ; 514 14 ; 514 16 ; 530317 ; 530326 ; 530327 ; 530328 ; 530330 ;
Abstract

TNF.alpha. antagonist compounds and methods of using the same are disclosed. The compounds comprise a molecular surface that is substantially similar to at least one molecular surface of human TNF.alpha.. The compounds bind to TNF receptors but do not produce the same biological effect as that which occurs when TNF.alpha. binds to a TNF receptor. Methods of inhibiting tumor necrosis factor activity are disclosed. The methods comprise the step of contacting tumor necrosis factor alpha with a TNF.alpha. antagonist. Methods of treating individuals suspected of suffering from or being susceptible to a disease or disorder mediated by tumor necrosis factor-alpha activity are disclosed. The methods comprise the step of administering to said individual a therapeutically effective amount of a TNF.alpha. antagonist.


Find Patent Forward Citations

Jameson, Bradford. (2000). Tumor necrosis factor inhibitors (U.S. Patent No. 6107273). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6107273

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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