The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2000
Filed:
Feb. 13, 1998
Applicant:
Inventors:
Mukund Prahalada Sibi, Fargo, ND (US);
John Joseph Shay, Fargo, ND (US);
Craig Peter Jasperse, Moorhead, MN (US);
Mei Liu, Fargo, ND (US);
Assignee:
North Dakota State University, Fargo, ND (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
544 97 ; 544316 ; 546243 ; 546221 ; 548239 ; 548220 ; 548229 ; 548257 ;
Abstract
A method for the preparation of .beta.-amino acid compounds is provided. The method includes contacting an amine nucleophile with an .alpha.,.beta.-unsaturated amide compound in the presence of a chiral Lewis acid complex. The chiral Lewis acid complex is formed from an azophilic metal salt and a chiral bisoxazolinylmethane compound. The selective amidolysis of one enantiomer of the .beta.-aminoamide product is also described.