The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2000
Filed:
Jun. 07, 1995
Applicant:
Inventors:
James A Trofatter, Charlestown, MA (US);
Mia M MacCollin, Medford, MA (US);
James F Gusella, Framingham, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
435 691 ; 4351721 ; 4353201 ; 514 12 ; 935 62 ; 530350 ; 5303871 ; 5303873 ; 5303877 ;
Abstract
A novel tumor suppressor protein, merlin, is described, including DNA sequences encoding merlin, and recombinant vectors and hosts capable of expressing merlin. Method for the diagnosis and treatment of merlin-associated tumors, and for the diagnosis and treatment of the disease neurofibromatosis 2 (NF2) are also provided.