The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2000

Filed:

Nov. 26, 1997
Applicant:
Inventors:

William R Kem, Gainesville, FL (US);

Michael W Pennington, Cherry Hill, NJ (US);

Raymond S Norton, Ivanhoe, AU;

K George Chandy, Laguna Beach, CA (US);

Katalin Kalman, Irvine, CA (US);

Assignees:

The University of Florida, Gainesville, FL (US);

Bachem Bioscience, Ing., King of Prussia, PA (US);

Biomolecular Research Institute, Parkville, AU;

Regents of the University of California, Oakland, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; A61K / ; C07K / ; A01N / ;
U.S. Cl.
CPC ...
435-724 ; 514 12 ; 514-9 ; 514-2 ; 4241851 ; 530300 ; 530324 ; 530855 ;
Abstract

Disclosed are methods and compositions comprising DNA segments, and proteins derived from sea anemone species. More particularly, it concerns the novel ShK toxin, ShK toxin analogs, chemically-modified toxin analogs, and nucleic acid segments encoding the ShK toxin from Stichodactyla helianthus. Various methods for making and using these DNA segments, DNA segments encoding synthetically-modified ShK toxins, and native and synthetic ShK peptides are disclosed, such as, for example, the use of DNA segments as diagnostic probes and templates for protein production, and the use of proteins, fusion protein carriers and peptides in various immunological and diagnostic applications.


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