The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2000

Filed:

May. 31, 1996
Applicant:
Inventors:

David H Walker, Galveston, TX (US);

Xue-Jie Yu, Galveston, TX (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
435 691 ; 435 697 ; 4352523 ; 4353201 ; 530350 ; 5303871 ; 536 231 ; 536 235 ; 536 234 ; 536 2433 ; 536 2431 ; 536 2432 ; 536 243 ; 536 245 ; 4242341 ;
Abstract

Disclosed is an isolated gene encoding a 120 kDa immunodominant antigen of Ehrlichia chaffeensis. The 120-kDa protein is one of the immunodominant proteins of E. chaffeensis that stimulates production of specific antibodies in infected humans. Also disclosed are the amino acid sequence of the 120 kDa antigen. Methods of producing a recombinant 120 kDa antigen and therapeutic methods of use of the antigen are also disclosed.


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