The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 1999
Filed:
Aug. 20, 1997
Applicant:
Inventors:
Eileen Landrum, Miami, FL (US);
Adry Galiounghi, Miami Lakes, FL (US);
Nancy Garcia, Miami, FL (US);
Ursino Del Valle, Hialeah, FL (US);
Frank J Lucas, Boca Raton, FL (US);
Assignee:
Coulter International Corp., Miami, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ;
U.S. Cl.
CPC ...
435 23 ; 435 24 ; 435-4 ; 435968 ; 435 29 ; 435 34 ;
Abstract
The ability to determine the stage or pathway of cysteine proteases in a single cell assay has long been desired as a material event in apoptosis. The present invention relates to a method and assay reagents for determining enzyme activity and relating said activity to the apoptotic pathway. In addition, the method find utility in distinguishing apoptotic activity from necrotic activity.