The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 1999

Filed:

Nov. 05, 1996
Applicant:
Inventors:

Roland Ellwood Dolle, III, King of Prussia, PA (US);

Tao Guo, Somerset, NJ (US);

Theodore Otto Johnson, Jr, Plainsboro, NJ (US);

Hitesh K Patel, North Brunswick, NJ (US);

Shiwei Tao, Plainsboro, NJ (US);

Zhen Min He, Princeton, NJ (US);

Assignee:

Pharmacopeia, Inc., Princeton, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ; C07C / ;
U.S. Cl.
CPC ...
436518 ; 436523 ; 436524 ; 435-71 ; 564193 ;
Abstract

Combinatorial chemical libraries of Formula I ##STR1## and methods for their preparation are disclosed. The libraries allow one to screen large numbers of compounds for a desired biological activity with relative ease. The libraries may be tagged or untagged. In preferred libraries, Y is the residue of an N-acylated amino acid, a substituted 4-aminoproline or a substituted piperazinealkanoic acid. The use of the libraries to discover biologically active compounds is also disclosed.


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