The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 1999

Filed:

Mar. 31, 1997
Applicant:
Inventors:

Bernhard H Weigl, Seattle, WA (US);

Paul Yager, Seattle, WA (US);

James P Brody, Seattle, WA (US);

Mark R Holl, Seattle, WA (US);

Margaret Kenny, Edmonds, WA (US);

David Schutte, Auburn, WA (US);

Gregory Hixson, Seattle, WA (US);

M Diane Zebert, Seattle, WA (US);

Andrew Kamholz, Seattle, WA (US);

Caicai Wu, Seattle, WA (US);

Eric Altendorf, Seattle, WA (US);

Assignee:

University of Washington, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436 34 ; 436172 ; 436177 ; 436180 ; 422 81 ;
Abstract

A channel-cell system is provided for detecting the presence and/or measuring the presence of analyte particles in a sample stream comprising: a) a laminar flow channel; b) two inlets in fluid connection with the laminar flow channel for respectively conducting into the laminar flow channel (1) an indicator stream which may comprise an indicator substance which indicates the presence of the analyte particles by a detectable change in property when contacted with the analyte particles, and (2) the sample stream; c) wherein the laminar flow channel has a depth sufficiently small to allow laminar flow of the streams and a length sufficient to allow particles of the analyte to diffuse into the indicator stream to the substantial exclusion of the larger particles in the sample stream to form a detection area; and d) an outlet for conducting the streams out of the laminar flow channel to form a single mixed stream.


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