The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 1999
Filed:
Aug. 26, 1996
Applicant:
Inventors:
Frank Mercurio, San Diego, CA (US);
Hengyi Zhu, San Diego, CA (US);
Miguel Barbosa, San Diego, CA (US);
Assignee:
Signal Pharmaceuticals, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ;
U.S. Cl.
CPC ...
435194 ; 530350 ; 530352 ;
Abstract
Compositions and methods are provided for treating NF-.kappa.B-related conditions. In particular, the invention provides a stimulus-inducible I.kappa.B.alpha. kinase complex, and components and variants thereof. I.kappa.B.alpha. kinase complex may be used, for example, to identify antibodies and other agents that inhibit or activate signal transduction via the NF-.kappa.B cascade. I.kappa.B.alpha. kinase complex, components thereof and/or such agents may also be used for the treatment of diseases associated with NF-.kappa.B activation.