The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 1999

Filed:

Sep. 01, 1994
Applicant:
Inventors:

Bert Vogelstein, Baltimore, MD (US);

Kenneth W Kinzler, Baltimore, MD (US);

Michael I Sherman, Glen Ridge, NJ (US);

Assignees:

Johns Hopkins University, Baltimore, MD (US);

Genzyme Corporation, Framingham, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; G01N / ; G01N / ; C07H / ;
U.S. Cl.
CPC ...
435-6 ; 435-723 ; 436 63 ; 436 64 ; 536 231 ; 536 241 ;
Abstract

Specific sequences in the human genome are the sites of strong binding of wild-type p53 protein, but not mutant forms of the protein. These sequences are used diagnostically to detect cells in which the amount of wild-type p53 is diminished. The sequences can also be used to screen for agents which correct for loss of wild-type p53 to DNA in cancer cells.


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Vogelstein, Bert. (1999). Sequence specific dna binding by p53 (U.S. Patent No. 5955263). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5955263

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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