The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 1999
Filed:
Aug. 01, 1995
Michael F Kozempel, Hatfield, PA (US);
Kevin B Hicks, Malvern, PA (US);
Michael J Kurantz, Maple Shade, NJ (US);
James C Craig, Maple Glen, PA (US);
Abstract
A method is described for the preparation of lactulose by isomerizing lactose to lactulose, followed by complexing lactulose to boric acid. The isomerization reaction is carried out in alkaline solution, and it is followed by splitting the lactulose-borate complex in acidic solution and separating the two components. Separation is achieved by crystallizing boric acid, filtering the crystals out of the product mixture, evaporating the product mixture to form a concentrate, recirculating the concentrate to the crystallization step where it is mixed with fresh reaction mixture in order to provide volume and nuclei for the crystallization of the boric acid in the reaction mixture, then passing the resulting mixture through another filtration step followed by an additional separation step by column chromatography.