The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 1998
Filed:
Dec. 12, 1996
Applicant:
Inventors:
Chi-Huey Wong, Rancho Santa Fe, CA (US);
Thomas G Marron, Grayslake, IL (US);
Thomas J Woltering, Weil am Rhein, DE;
Gabriele Weitz-Schmidt, Bad Krozingen, DE;
Assignee:
The Scripps Research Institute, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; A61K / ;
U.S. Cl.
CPC ...
536 53 ; 514 23 ; 514 53 ; 530322 ;
Abstract
Sialyl Lewis X mimetics based on mannose glycosides are synthesized and shown to mimic the configuration and essential functional groups of sialyl Lewis X in space. The mannose based mimetics exhibit comparable biological activity as sialyl Lewis X in the E- selectin binding assay and can be employed for blocking neutrophil inflamatory conditions.