The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 1998

Filed:

Dec. 14, 1994
Applicant:
Inventors:

Virgil B Lawlis, Jr, San Mateo, CA (US);

Henry G Heinsohn, Pacifica, CA (US);

Enrique F Baliu, San Francisco, CA (US);

Assignee:

Genencor International, Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12P / ;
U.S. Cl.
CPC ...
435183 ; 435171 ; 435 711 ; 435814 ; 435911 ; 435917 ; 435942 ; 4352568 ; 4352541 ; 435244 ; 530412 ; 530823 ; 530824 ; 424605 ;
Abstract

This invention provides a method for killing cells in fermentation mixtures in order to prepare the fermentation mixture for processing to recover or extract a desired product from the fermentation mixture. A preferred method of this invention comprises in either order, adjusting the pH of the fermentation mixture to a value equal to or less than about two pH units below the pK.sub.a of the compatible organic acid using a mineral acid, and adding a sufficient amount of a compatible organic acid and/or organic acid salt to the mixture to effect a substantially complete cell kill. The method of this invention is useful for killing microorganisms such as yeast, bacteria or fungi in any culture or fermentation mixture and is particularly useful in systems where it is desired to kill the cells without lysing them.


Find Patent Forward Citations

Lawlis, Jr, Virgil. (1998). Method for killing cells without lysis and enzyme recovery (U.S. Patent No. 5801034). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5801034

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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