The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 1998
Filed:
Aug. 15, 1996
Applicant:
Inventors:
Tianbao Lu, Exton, PA (US);
Carl R Illig, Phoenixville, PA (US);
Bruce E Tomczuk, Collegeville, PA (US);
Richard M Soll, Lawrenceville, NJ (US);
Nalin L Subasinghe, West Chester, PA (US);
Roger F Bone, Bridgewater, NJ (US);
Assignee:
3-Dimensional Pharmaceuticals, Inc., Exton, PA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07F / ; C07D / ; C07C / ;
U.S. Cl.
CPC ...
514255 ; 514317 ; 514330 ; 514331 ; 514603 ; 514604 ; 514634 ; 514822 ; 544398 ; 544399 ; 544400 ; 544402 ; 546 21 ; 546229 ; 546230 ; 546231 ; 564237 ;
Abstract
Compounds of the formula: ##STR1## wherein R.sup.1 --R.sup.4, R.sup.7 --R.sup.8, R.sup.a, R.sup.b, R.sup.c, Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit a number of proteolytic enzymes are described. Also described are methods for preparing the compounds of Formula I.