The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 1998
Filed:
Jan. 17, 1995
Applicant:
Inventors:
William K Holloman, Yorktown Heights, NY (US);
Eric B Kmiec, Malvern, PA (US);
Assignee:
Thomas Jefferson University, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ;
U.S. Cl.
CPC ...
4353201 ; 536 232 ;
Abstract
The invention concerns genes encoding recombinases that can be used to promote homologous recombination in eukaryotic cells and expression vectors that can be used to transiently express recombinases in target cells. One embodiment of the invention encompasses genetically engineered nucleic acids that encode a non-naturally occurring recombinase that causes a greater rate of recombination than does the naturally occurring recombinase. Recombinases from Ustilago maydis, Saccharomyces cerevisiae are specifically included in the invention.